InterPro domain: IPR042532

General Information

  • Identifier IPR042532
  • Description Exocyst complex component EXOC3/Sec6, C-terminal domain
  • Number of genes 143
  • Gene duplication stats Loading...

Abstract

Sec6 is a component of the multiprotein exocyst complex. Sec6 interacts with Sec8, Sec10 and Exo70. These exocyst proteins localise to regions of active exocytosis-at the growing ends of interphase cells and in the medial region of cells undergoing cytokinesis-in an F-actin-dependent and exocytosis-independent manner [ 1 ].

This superfamily represents the C-terminal domain found in EXOC3/Sec6. Structurally, this domain consists of multiple helical bundles [ 2 ].


1. The multiprotein exocyst complex is essential for cell separation in Schizosaccharomyces pombe. Mol. Biol. Cell 13, 515-29
2. The structure of the exocyst subunit Sec6p defines a conserved architecture with diverse roles. Nat. Struct. Mol. Biol. 13, 555-6

Species distribution

Gene table