InterPro domain: IPR042321

This entry represents a group of proteins from fungi. Ima1 couples centromeres to the nuclear envelope, thus contributing to their association with the microtubule organizing centre attachment site and to the positioning of the nucleus at the cell centre by microtubules [ 1 , 2 ].

1. A network of nuclear envelope membrane proteins linking centromeres to microtubules. Cell 134, 427-38
2. The inner nuclear membrane proteins Man1 and Ima1 link to two different types of chromatin at the nuclear periphery in S. pombe. Nucleus 3, 77-87