InterPro domain: IPR042237

General Information

  • Identifier IPR042237
  • Description Putative peptidyl-tRNA hydrolase PTRHD1
  • Number of genes 116
  • Gene duplication stats Loading...

Abstract

PTRHD1 is predicted to be peptidyl-tRNA hydrolase due to their amino acid sequence similarity. However, its real function is still not clear. Mutations in PTRHD1 cause autosomal-recessive juvenile parkinsonism and intellectual disability [ 1 ].


1. PTRHD1 Loss-of-function mutation in an african family with juvenile-onset Parkinsonism and intellectual disability. Mov. Disord. 33, 1814-1819

Species distribution

Gene table