InterPro domain: IPR042171

General Information

  • Identifier IPR042171
  • Description Acyl-CoA thioesterase, double hotdog domain
  • Number of genes 177
  • Gene duplication stats Loading...

Abstract

This superfamily includes TE4 thioesterases that contain a hotdog domain. Studies on TesB from Y. pestis provide insights into the TE4 thioesterase family. It is organised in an octameric arrangement of hotdog domains (a tetramer of double-hotdog protomers) which is not present in any other thioesterase family [ 1 ].


1. Structural and functional characterization of TesB from Yersinia pestis reveals a unique octameric arrangement of hotdog domains. Acta Crystallogr. D Biol. Crystallogr. 71, 986-95

Species distribution

Gene table