InterPro domain: IPR042163

General Information

  • Identifier IPR042163
  • Description PHD finger protein 12
  • Number of genes 233
  • Gene duplication stats Loading...
  • Associated GO terms GO:0045892   GO:0003714  

Abstract

PHF12, also known as Pf1, is a PHD zinc finger protein that binds TLE (transducin-like enhancer) in an mSin3A-independent manner and recruits functional TLE complexes to repress transcription [ 1 ].


1. Pf1, a novel PHD zinc finger protein that links the TLE corepressor to the mSin3A-histone deacetylase complex. Mol. Cell. Biol. 21, 4110-8

Species distribution

Gene table