InterPro domain: IPR042079

General Information

  • Identifier IPR042079
  • Description ATP synthase, F1 beta subunit superfamily
  • Number of genes 230
  • Gene duplication stats Loading...

Abstract

The NMR solution structure of the protein in SDS micelles was found to contain two helices, an N-terminal amphipathic alpha-helix and a C-terminal alpha-helix separated by a large unstructured internal domain. The N-terminal alpha-helix is the Tom20 receptor binding site whereas the C-terminal alpha-helix is located upstream of the mitochondrial processing peptidase cleavage site [ 1 ].

This superfamily includes the F1 beta subunit of ATP synthase.F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c.


1. NMR solution structure of the mitochondrial F1beta presequence from Nicotiana plumbaginifolia. J. Mol. Biol. 336, 1129-40

Species distribution

Gene table

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