InterPro domain: IPR041806
General Information
- Identifier IPR041806
- Description Polyadenylate-binding protein-interacting protein 5/6/7, CUE domain
- Number of genes 322
- Gene duplication stats Loading...
Abstract
This entry represents the CUE domain found in a group of plant proteins, including CID5/6/7. CID7 contains an N-terminal PABC-interacting domain (PAM2 or PABP-interacting motif 2) which is also found in the human Paip1 and Paip2. It functions as an interaction partner of the PABC domain of Arabidopsis thaliana Poly(A)-binding proteins. It also harbours an ubiquitin-associated (UBA)-like CUE domain and a C-terminal small MutS-related (SMR) domain [ 1 ]. CID5 (also known as IPD1) has been shown to regulate the endocycle leading to hypocotyl elongation [ 2 ]. The biological function of CID6 is unclear.
1. Four distinct classes of proteins as interaction partners of the PABC domain of Arabidopsis thaliana Poly(A)-binding proteins. Mol. Genet. Genomics 272, 651-65
2. Light-dependent polyploidy control by a CUE protein variant in Arabidopsis. Plant Mol. Biol. 61, 817-28