InterPro domain: IPR041628

This entry represents the alpha helical AAA+ lid domain that is found to the C terminus of AAA domains.

Proteins containing this domain include magnesium-chelatase subunits, such as ChlI and ChlD. The plant magnesium-chelatase is a complex of three subunits, CHLI, CHLD and CHLH. The reaction takes place in two steps, with an ATP-dependent activation followed by an ATP-dependent chelation step [ 1 ]. This domain can also be found in MoxR, a putative AAA-type ATPase enzymatic complex assembly chaperone [ 2 ].

1. Functional analysis of Arabidopsis thaliana isoforms of the Mg-chelatase CHLI subunit. Photochem. Photobiol. Sci. 7, 1188-95
2. MoxR AAA+ ATPases: a novel family of molecular chaperones? J. Struct. Biol. 156, 200-9