InterPro domain: IPR041591

General Information

  • Identifier IPR041591
  • Description OCRE domain
  • Number of genes 443
  • Gene duplication stats Loading...

Abstract

The OCtamer REpeat (OCRE) has been annotated as a 42-residue sequence motif with 12 tyrosine residues in the spliceosome trans-regulatory elements RBM5 and RBM10 (RBM [RNA-binding motif]), which are known to regulate alternative splicing of Fas and Bcl-x pre-mRNA transcripts [ 1 ]. The structure of the domain consists of an anti-parallel arrangement of six beta strands.


1. Nuclear Magnetic Resonance Structure of a Novel Globular Domain in RBM10 Containing OCRE, the Octamer Repeat Sequence Motif. Structure 24, 158-164

Species distribution

Gene table

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