InterPro domain: IPR041412

General Information

  • Identifier IPR041412
  • Description Xrn1, helical domain
  • Number of genes 543
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Abstract

This helical domain is part of the Xrn1 catalytic core [ 1 ]. Xrn1 is a cytoplasmic 5'-3' exonuclease that degrades decapped mRNAs. This domain can also be found in Xrn2 [ 2 ].


1. Coupled 5' nucleotide recognition and processivity in Xrn1-mediated mRNA decay. Mol. Cell 41, 600-8
2. The yeast 5'-3' exonuclease Rat1p functions during transcription elongation by RNA polymerase II. Mol. Cell 37, 580-7

Species distribution

Gene table