InterPro domain: IPR041355

General Information

  • Identifier IPR041355
  • Description Pre-SET CXC domain
  • Number of genes 247
  • Gene duplication stats Loading...

Abstract

This domain is found to the N terminus of the SET domain in the EZH2 protein [ 1 ]. It is a zinc binding domain.


1. Structure of the catalytic domain of EZH2 reveals conformational plasticity in cofactor and substrate binding sites and explains oncogenic mutations. PLoS ONE 8, e83737

Species distribution

Gene table