InterPro domain: IPR041190

General Information

  • Identifier IPR041190
  • Description Midasin AAA lid domain 5
  • Number of genes 111
  • Gene duplication stats Loading...

Abstract

This entry represents the alpha helical AAA+ lid domain that is found to the C terminus of AAA domains [ 1 ]. This lid domain is found in midasin, which is a nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits [ 2 ].


1. Expression and genomic analysis of midasin, a novel and highly conserved AAA protein distantly related to dynein. BMC Genomics 3, 18
2. The AAA ATPase MDN1 Acts as a SUMO-Targeted Regulator in Mammalian Pre-ribosome Remodeling. Mol. Cell 64, 607-615

Species distribution

Gene table

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