InterPro domain: IPR041094

General Information

  • Identifier IPR041094
  • Description Brr2, N-terminal helicase PWI domain
  • Number of genes 181
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Abstract

This domain is found in spliceosomal RNA helicase Brr2. Brr2 is required for the assembly of a catalytically active spliceosome on a messenger RNA precursor. The domain is found in the N-terminal region and is non-canonically PWI-like. The PWI-like domain is thought to be involved in protein-protein interactions [ 1 ].


1. A noncanonical PWI domain in the N-terminal helicase-associated region of the spliceosomal Brr2 protein. Acta Crystallogr. D Biol. Crystallogr. 71, 762-71

Species distribution

Gene table

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