InterPro domain: IPR040881

This domain is present in bacterial ureases and corresponds to the gap region between the C terminus of the beta-chain Urease beta subunit and the N terminus of the alpha-chain Urease alpha-subunit, N-terminal domain [ 1 ]. It is suggested that this region is required for the stability of the putative transmembrane beta-barrel, and might be the reason for bacterial urease (B. pasteurii) not being lethal to insects [ 2 ].

1. Jaburetox-2Ec: an insecticidal peptide derived from an isoform of urease from the plant Canavalia ensiformis. Peptides 28, 2042-50
2. Crystal structure of the first plant urease from jack bean: 83 years of journey from its first crystal to molecular structure. J. Mol. Biol. 400, 274-83