InterPro domain: IPR040780

General Information

  • Identifier IPR040780
  • Description 6S proteasome subunit Rpn6, C-terminal helix domain
  • Number of genes 200
  • Gene duplication stats Loading...

Abstract

This is the C-terminal helix domain found in Rpn6, a component of the 26S proteasome. The C-terminal helices are essential for lid assembly [ 1 , 2 ].


1. Formation of an intricate helical bundle dictates the assembly of the 26S proteasome lid. Structure 21, 1624-35
2. Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome. Proc. Natl. Acad. Sci. U.S.A. 111, 5544-9

Species distribution

Gene table