InterPro domain: IPR040608

This family includes Snf8 and Vps36. Vps36 is involved in Golgi to endosome trafficking. Snf8 is a component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs [ 1 ].

1. Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body. Dev. Cell 3, 283-9