InterPro domain: IPR040598

General Information

  • Identifier IPR040598
  • Description UPF0113, pre-PUA domain
  • Number of genes 153
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Abstract

Protein KD93 is a NIP7 homologue and belongs to the UPF0113 family. The overall fold of KD93 consists of two interlinked alpha/beta domains. The C-terminal domain resembles the PUA domain of some RNA modification enzymes, especially that of archaeosine tRNA-ribosyltransferase (ArcTGT), suggesting a possible molecular function related to RNA binding [ 1 ]. This entry represents the N-terminal, pre-PUA domain.


1. Crystal structure of KD93, a novel protein expressed in human hematopoietic stem/progenitor cells. J. Struct. Biol. 148, 370-4

Species distribution

Gene table

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