InterPro domain: IPR040447

General Information

  • Identifier IPR040447
  • Description Rrp7, RRM-like N-terminal domain
  • Number of genes 1
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Abstract

Ribosomal RNA-processing protein 7 (RRP7) is an essential protein in yeast that is involved in pre-rRNA processing and ribosome assembly [ 1 ]. It is speculated to be required for correct assembly of rpS27 into the pre-ribosomal particle [ 2 , 2 ].

This domain corresponds to the N-terminal RNA-binding domain found in the Rrp7 protein. It has an RRM-like fold with a circular permutation [ 3 ].


1. Functional analysis of Rrp7p, an essential yeast protein involved in pre-rRNA processing and ribosome assembly. Mol. Cell. Biol. 17, 5023-32
2. The 90S preribosome is a multimodular structure that is assembled through a hierarchical mechanism. Mol. Cell. Biol. 27, 5414-29
3. An RNA-binding complex involved in ribosome biogenesis contains a protein with homology to tRNA CCA-adding enzyme. PLoS Biol. 11, e1001669

Species distribution

Gene table

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