InterPro domain: IPR040390

JASMONATE ZIM-domain (JAZ) proteins act as repressors of jasmonate (JA) signaling [ 1 ]. The ZIM domain recruits the co-repressors NINJA and TOPLESS to JAZ-bound transcription factors, and contains a highly conserved TIF[F/Y]XG motif that defines the larger family of TIFY proteins to which JAZs belong. This family consists of TIFY/JAZ proteins, and also includes JAZ13 (At3g22275), a non-TIFY JAZ protein that is a repressor of JA signaling [ 2 ]. Some of the members of the TIFY/JAZ family, such as TIFY8, are not involved in JA signaling. TIFY8 is found in protein complexes involved in regulation of dephosphorylation, deubiquitination and O-linked N-acetylglucosamine modification, suggesting an important role in nuclear signal transduction [ 3 ].

1. The JAZ family of repressors is the missing link in jasmonate signalling. Nature 448, 666-71
2. Repression of jasmonate signaling by a non-TIFY JAZ protein in Arabidopsis. Plant J. 82, 669-79
3. The non-JAZ TIFY protein TIFY8 from Arabidopsis thaliana is a transcriptional repressor. PLoS ONE 9, e84891