InterPro domain: IPR040267

This entry includes a group of plant F-box proteins, including EID1 and EDL1/2/3 from Arabidopsis. EID1 is part of the SCF (ASK-cullin-F-box) E3 ubiquitin ligase complex [ 1 , 2 ]. It functions as a negative regulator in far-red light signaling downstream of the phyA in Arabidopsis [ 3 ]. The allelic variation of the tomato homologue of the Arabidopsis EID1 has been linked to slower circadian rhythms [ 4 ]. EID1-like protein 3 (EDL3) is involved in the regulation of abscisic acid signalling [ 5 ].

1. Functional analysis of EID1, an F-box protein involved in phytochrome A-dependent light signal transduction. Plant J. 45, 423-38
2. Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis. Plant J. 34, 753-67
3. The histidine kinase-related domain of Arabidopsis phytochrome a controls the spectral sensitivity and the subcellular distribution of the photoreceptor. Plant Physiol. 150, 1297-309
4. Domestication selected for deceleration of the circadian clock in cultivated tomato. Nat. Genet. 48, 89-93
5. EDL3 is an F-box protein involved in the regulation of abscisic acid signalling in Arabidopsis thaliana. J. Exp. Bot. 62, 5547-60