InterPro domain: IPR040153

General Information

  • Identifier IPR040153
  • Description Respiratory supercomplex factor 2, mitochondrial
  • Number of genes 276
  • Gene duplication stats Loading...

Abstract

Rcf2 is a subunit of cytochrome c oxidase that plays a role in assembly of respiratory supercomplexes [ 1 , 2 ].


1. Rcf1 mediates cytochrome oxidase assembly and respirasome formation, revealing heterogeneity of the enzyme complex. Cell Metab. 15, 336-47
2. Rcf1 and Rcf2, members of the hypoxia-induced gene 1 protein family, are critical components of the mitochondrial cytochrome bc1-cytochrome c oxidase supercomplex. Mol. Cell. Biol. 32, 1363-73

Species distribution

Gene table