InterPro domain: IPR040096

General Information

  • Identifier IPR040096
  • Description RAB6A-GEF complex partner protein 1
  • Number of genes 137
  • Gene duplication stats Loading...
  • Associated GO terms GO:0034066   GO:0006886  

Abstract

Ric1 is part of the RIC1-RGP1 complex that acts as a guanine nucleotide exchange factor (GEF) for Rab6 GTPase, which is important for normal Golgi structure and function [ 1 , 2 ].


1. Ric1-Rgp1 complex is a guanine nucleotide exchange factor for the late Golgi Rab6A GTPase and an effector of the medial Golgi Rab33B GTPase. J. Biol. Chem. 287, 42129-37
2. Ric1p and Rgp1p form a complex that catalyses nucleotide exchange on Ypt6p. EMBO J. 19, 4885-94

Species distribution

Gene table