InterPro domain: IPR040050
General Information
- Identifier IPR040050
- Description Zinc finger protein 830-like
- Number of genes 133
- Gene duplication stats Loading...
- Associated GO terms GO:0003676 GO:0008270 GO:0005681
Abstract
Zinc finger protein 830 (ZNF830; also known as coiled-coil domain-containing protein 16 or CCDC16) contains a C2H2-type zinc finger and a coiled-coil region. It is a component of the XAB2 complex, which binds RNA [ 1 ], and a component of a pentameric intron-binding complex that is pre-assembled and then incorporated into the spliceosome [ 2 ].
This entry also includes protein ABA AND ROS SENSITIVE 1 (ARS1) from Arabidopsis. It is essential for seed germination and ROS homeostasis in response to ABA and oxidative stress [ 3 ].
1. Isolation of XAB2 complex involved in pre-mRNA splicing, transcription, and transcription-coupled repair. J. Biol. Chem. 283, 940-50
2. The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes. Nat. Struct. Mol. Biol. 22, 138-44
3. The Arabidopsis a zinc finger domain protein ARS1 is essential for seed germination and ROS homeostasis in response to ABA and oxidative stress. Front Plant Sci 6, 963