InterPro domain: IPR040050

General Information

  • Identifier IPR040050
  • Description Zinc finger protein 830-like

Abstract

Zinc finger protein 830 (ZNF830; also known as coiled-coil domain-containing protein 16 or CCDC16) contains a C2H2-type zinc finger and a coiled-coil region. It is a component of the XAB2 complex, which binds RNA [ 1 ], and a component of a pentameric intron-binding complex that is pre-assembled and then incorporated into the spliceosome [ 2 ].

This entry also includes protein ABA AND ROS SENSITIVE 1 (ARS1) from Arabidopsis. It is essential for seed germination and ROS homeostasis in response to ABA and oxidative stress [ 3 ].


1. Isolation of XAB2 complex involved in pre-mRNA splicing, transcription, and transcription-coupled repair. J. Biol. Chem. 283, 940-50
2. The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes. Nat. Struct. Mol. Biol. 22, 138-44
3. The Arabidopsis a zinc finger domain protein ARS1 is essential for seed germination and ROS homeostasis in response to ABA and oxidative stress. Front Plant Sci 6, 963

Species distribution

Gene table

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