InterPro domain: IPR040007

General Information

  • Identifier IPR040007
  • Description THO complex subunit 2

Abstract

THO/TREX, a nuclear protein complex conserved from yeast to humans, plays an important role in mRNP biogenesis connecting transcription elongation, mRNA export and preventing genetic instability. THO could be relevant to different mRNA processing steps, including the 3'-end formation, transcript release and export [ 1 ]. This entry represents the Tho2 subunit of the THO/TREX complex.


1. New clues to understand the role of THO and other functionally related factors in mRNP biogenesis. Biochim. Biophys. Acta 1819, 514-20

Species distribution

Gene table