InterPro domain: IPR039845

General Information

  • Identifier IPR039845
  • Description PSME3-interacting protein
  • Number of genes 120
  • Gene duplication stats Loading...

Abstract

PIP30/FAM192A acts as a regulator of PA28-gamma, a nuclear activator of the 20S proteasome. PIP30 favours PA28-gamma interaction with the 20S proteasome while inhibiting its association with coilin, a central component of nuclear Cajal bodies [ 1 ].


1. PIP30/FAM192A is a novel regulator of the nuclear proteasome activator PA28γ. Proc. Natl. Acad. Sci. U.S.A. 115, E6477-E6486

Species distribution

Gene table