InterPro domain: IPR039785
General Information
- Identifier IPR039785
- Description Deubiquitinating enzyme MINDY-3/4
- Number of genes 144
- Gene duplication stats Loading...
- Associated GO terms GO:0004843 GO:1990380 GO:0071108
Abstract
Deubiquitinating enzymes (DUBs) remove ubiquitin (Ub) from Ub-conjugated substrates to regulate the functional outcome of ubiquitylation. This entry includes MINDY-3/4. They belong to the MINDY (motif interacting with Ub-containing novel DUB) family (peptidase family C121), whose members are deubiquitinating enzymes releasing Lys48-linked ubiquitin [ 1 ].
1. MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes. Mol. Cell 63, 146-55
Species distribution
Gene table
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