InterPro domain: IPR039772

Proteins in this entry contain a Bin3-type S-adenosyl-L-methionine binding domain, proteins include:

• Drosophila melanogaster 7SK snRNA methylphosphate capping enzyme bin3, interacting with bicoid/bcd [ 1 ], probable RNA methyltransferase CG1239 and CG11342
• 7SK snRNA methylphosphate capping enzyme (MePCE) or Bicoid-interacting protein 3 homologue (Bin3 homolog), a S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilise it [ 2 ]
• RNA 5'-monophosphate methyltransferase BCDIN3D [ 3 ]
• Arabidopsis thaliana probable RNA methyltransferase At5g51130
• Schizosaccharomyces pombe probable RNA methyltransferase C2A9.10
• Caenorhabditis elegans probable methyltransferase Y17G7B.18

1. The Bin3 RNA methyltransferase is required for repression of caudal translation in the Drosophila embryo. Dev. Biol. 352, 104-15
2. Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Mol. Cell 27, 262-74
3. Human RNA methyltransferase BCDIN3D regulates microRNA processing. Cell 151, 278-88