InterPro domain: IPR039740
General Information
- Identifier IPR039740
- Description CCR4-NOT transcription complex subunit 10
- Number of genes 180
- Gene duplication stats Loading...
- Associated GO terms GO:0030014
Abstract
CNOT10 is part of the CCR4-NOT complex, a major cellular mRNA deadenylase linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. CNOT10 is essential for the integrity of the CCR4-NOT complex and for degradation of many mRNAs [ 1 ].
1. Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAs. Nucleic Acids Res. 41, 1211-22
Species distribution
Gene table
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