InterPro domain: IPR039740

General Information

  • Identifier IPR039740
  • Description CCR4-NOT transcription complex subunit 10
  • Number of genes 180
  • Gene duplication stats Loading...
  • Associated GO terms GO:0030014  

Abstract

CNOT10 is part of the CCR4-NOT complex, a major cellular mRNA deadenylase linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. CNOT10 is essential for the integrity of the CCR4-NOT complex and for degradation of many mRNAs [ 1 ].


1. Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAs. Nucleic Acids Res. 41, 1211-22

Species distribution

Gene table