InterPro domain: IPR039699

This entry includes the eukaryotic L30 subunit, the archaeal L7 subunit and the ribosome biogenesis protein RLP7 (ribosomal protein L7-like) from yeasts. RLP7 is required for the biogenesis of the 60S ribosomal subunit [ 1 ].

Ribosomal protein L30 is one of the proteins from the large ribosomal subunit. L30 belongs to a family of ribosomal proteins which, on the basis of sequence similarities [ 2 ], groups bacteria and archaea L30, yeast mitochondrial L33, and Drosophila melanogaster, Dictyostelium discoideum (Slime mold), fungal and mammalian L7 ribosomal proteins. L30 from bacteria are small proteins of about 60 residues, those from archaea are proteins of about 150 residues, and eukaryotic L7 are proteins of about 250 to 270 residues.

1. A nucleolar protein related to ribosomal protein L7 is required for an early step in large ribosomal subunit biogenesis. Proc. Natl. Acad. Sci. U.S.A. 97, 13027-32
2. Yeast ribosomal proteins: XIII. Saccharomyces cerevisiae YL8A gene, interrupted with two introns, encodes a homolog of mammalian L7. Nucleic Acids Res. 20, 1011-6