InterPro domain: IPR039690

General Information

  • Identifier IPR039690
  • Description U11/U12 small nuclear ribonucleoprotein 25kDa protein
  • Number of genes 378
  • Gene duplication stats Loading...
  • Associated GO terms GO:0005689   GO:0000398  

Abstract

U11 and U12 small nuclear ribonucleoprotein (snRNPs) bind U12-type pre-mRNAs as a preformed di-snRNP complex, simultaneously recognizing the 5' splice site and branchpoint sequence. SNRNP25 is a component of the U11/U12 snRNP complex [ 1 , 2 ]. Homologues are known from animals, plants and fungi.


1. The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. RNA 10, 929-41
2. Structural features important for the U12 snRNA binding and minor spliceosome assembly of Arabidopsis U11/U12-small nuclear ribonucleoproteins. RNA Biol 13, 670-9

Species distribution

Gene table