InterPro domain: IPR039660

General Information

  • Identifier IPR039660
  • Description Ribosomal protein L14
  • Number of genes 396
  • Gene duplication stats Loading...
  • Associated GO terms GO:0003723   GO:0003735  

Abstract

L14 is an eukaryote-specific ribosomal protein from the 60S ribosomal subunit, which is conserved in some but not all archaea. In yeast, L14 assembles in the nucleolus at an early stage into pre-60S particles [ 1 ]. Auto-antibodies to RPL14 in humans have been associated with systemic lupus erythematosus [ 2 ].


1. Ribosomal protein L14 contributes to the early assembly of 60S ribosomal subunits in Saccharomyces cerevisiae. Nucleic Acids Res. 46, 4715-4732
2. Autoantibody against ribosomal protein L14 in patients with systemic lupus erythematosus. Clin. Exp. Rheumatol. 20, 139-44

Species distribution

Gene table