InterPro domain: IPR039638
General Information
- Identifier IPR039638
- Description Mediator of RNA polymerase II transcription subunit 33A/B
- Number of genes 428
- Gene duplication stats Loading...
- Associated GO terms GO:0016592 GO:2000762
Abstract
This entry represents a group of plant proteins, including MED33A/B (RFR1/REF4) from Arabidopsis. MED33A/B are components of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. They are required for phenylpropanoid homeostasis in Arabidopsis [ 1 , 2 ].
1. REF4 and RFR1, subunits of the transcriptional coregulatory complex mediator, are required for phenylpropanoid homeostasis in Arabidopsis. J. Biol. Chem. 287, 5434-45
2. Semidominant mutations in reduced epidermal fluorescence 4 reduce phenylpropanoid content in Arabidopsis. Genetics 178, 2237-51
Species distribution
Gene table
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