InterPro domain: IPR039638

General Information

  • Identifier IPR039638
  • Description Mediator of RNA polymerase II transcription subunit 33A/B
  • Number of genes 428
  • Gene duplication stats Loading...
  • Associated GO terms GO:0016592   GO:2000762  

Abstract

This entry represents a group of plant proteins, including MED33A/B (RFR1/REF4) from Arabidopsis. MED33A/B are components of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. They are required for phenylpropanoid homeostasis in Arabidopsis [ 1 , 2 ].


1. REF4 and RFR1, subunits of the transcriptional coregulatory complex mediator, are required for phenylpropanoid homeostasis in Arabidopsis. J. Biol. Chem. 287, 5434-45
2. Semidominant mutations in reduced epidermal fluorescence 4 reduce phenylpropanoid content in Arabidopsis. Genetics 178, 2237-51

Species distribution

Gene table