InterPro domain: IPR039591

General Information

  • Identifier IPR039591
  • Description AP-5 complex subunit mu-1
  • Number of genes 115
  • Gene duplication stats Loading...

Abstract

AP5M1, also known as MUDENG, is part of AP-5, a probable fifth adaptor protein complex that may be involved in endosomal transport [ 1 ]. AP5M1 is involved in cell death signaling [ 2 , 3 ].


1. The fifth adaptor protein complex. PLoS Biol. 9, e1001170
2. MUDENG is cleaved by caspase-3 during TRAIL-induced cell death. Biochem. Biophys. Res. Commun. 435, 234-8
3. Characterization of MUDENG, a novel anti-apoptotic protein. Oncogenesis 5, e221

Species distribution

Gene table