InterPro domain: IPR039447

General Information

  • Identifier IPR039447
  • Description Urease accessory protein UreH-like, transmembrane domain
  • Number of genes 168
  • Gene duplication stats Loading...

Abstract

Urease is a nickel containing metalloenzyme that hydrolyses urea into ammonia [ 1 ]. This entry represents a transmembrane domain found in UreH, an urease accessory protein [ 2 ]. In Helicobacter pylori, UreH is part of the UreG/UreF/UreH complex that may be responsible for delivery of nickel ions into the urease active site [ 3 ].


1. Structure of UreG/UreF/UreH complex reveals how urease accessory proteins facilitate maturation of Helicobacter pylori urease. PLoS Biol. 11, e1001678
2. Cloning, sequencing, and expression of thermophilic Bacillus sp. strain TB-90 urease gene complex in Escherichia coli. J. Bacteriol. 176, 432-42

Species distribution

Gene table