InterPro domain: IPR039411

NSA2 is required for the maturation of 27S pre-rRNA in yeast [ 1 ]. It has been characterised in mammalian cells as a nucleolar protein that might play a role in the regulation of the cell cycle and in cell proliferation [ 2 ].

1. Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs. J. Biol. Chem. 281, 27099-108
2. NSA2, a novel nucleolus protein regulates cell proliferation and cell cycle. Biochem. Biophys. Res. Commun. 391, 651-8