InterPro domain: IPR039367

General Information

  • Identifier IPR039367
  • Description Initiation-specific alpha-1,6-mannosyltransferase Och1-like
  • Number of genes 4
  • Gene duplication stats Loading...
  • Associated GO terms GO:0000009  

Abstract

This entry includes Och1 and its homologue, Hoc1. Och1 is a alpha-1,6-mannosyltransferase involved in the N-linked oligosaccharide modification in the Golgi apparatus with the addition of mannose to the Man 8 GlcNAc 2 or Man 9 GlcNAc 2 endoplasmic reticulum intermediates [ 1 , 2 ]. Hoc1 is a subunit of the M-Pol II complex and possesses alpha-1,6-mannosyltransferase activity [ 3 ].


1. Schizosaccharomyces pombe och1(+) encodes alpha-1,6-mannosyltransferase that is involved in outer chain elongation of N-linked oligosaccharides. FEBS Lett. 489, 75-80
2. Saccharomyces cerevisiae alpha1,6-mannosyltransferase has a catalytic potential to transfer a second mannose molecule. FEBS J. 273, 5074-85
3. The Saccharomyces cerevisiae protein Mnn10p/Bed1p is a subunit of a Golgi mannosyltransferase complex. J. Biol. Chem. 274, 6579-85

Species distribution

Gene table