InterPro domain: IPR039326

PATRONUS (PANS1) is an Arabidopsis protein required for protection of meiotic centromeric cohesion [ 1 , 2 ]. It is also essential for growth adaptation to stress and required for mitotic onset control [ 3 ]. PANS2, a paralogue of PANS1, is not required for centromeric cohesion, but may have a redundant role with PANS1 in gametophytic and somatic development, possibly at mitosis [ 4 ]. At least one PANS homologue is present in all dicot species [ 5 ].

1. PATRONUS1 is expressed in meiotic prophase I to regulate centromeric cohesion in Arabidopsis and shows synthetic lethality with OSD1. BMC Plant Biol. 15, 201
2. SHUGOSHINs and PATRONUS protect meiotic centromere cohesion in Arabidopsis thaliana. Plant J. 77, 782-94
3. Arabidopsis COPPER MODIFIED RESISTANCE1/PATRONUS1 is essential for growth adaptation to stress and required for mitotic onset control. New Phytol. 209, 177-91
4. Centromeric cohesion is protected twice at meiosis, by SHUGOSHINs at anaphase I and by PATRONUS at interkinesis. Curr. Biol. 23, 2090-9