InterPro domain: IPR039206

This entry represents a group of plant proteins, including multiple organellar RNA editing factor 1-9 (MORF1-9) and ORRM1 from Arabidopsis, and DAG protein from Antirrhinum majus. DAG shares protein sequence similarity with MORFs and the N terminus of ORRM1. However, ORRM1 also contains a C-terminal RNA recognition motif (RRM), which is absent in DAG and MORFs. They are involvled in C-to-U RNA editing (deamination of cytidine to uridine), an essential step of RNA maturation in chloroplasts and mitochondria of land plants from bryophytes to angiosperms [ 1 , 2 ]. They interact selectively with diverse PPR (PLS-class of pentatricopeptide repeat) proteins, and these interactions are important for their RNA editing function. MORFs are required for RNA editing in mitochondria and plastids [ 3 ].

1. Functional divergence and origin of the DAG-like gene family in plants. Sci Rep 7, 5688
2. An RNA recognition motif-containing protein is required for plastid RNA editing in Arabidopsis and maize. Proc. Natl. Acad. Sci. U.S.A. 110, E1169-78
3. Multiple organellar RNA editing factor (MORF) family proteins are required for RNA editing in mitochondria and plastids of plants. Proc. Natl. Acad. Sci. U.S.A. 109, 5104-9