InterPro domain: IPR039169

This enty includes Abitram proteins. Abitram (also known as Simiate) functions in transcription regulation [ 1 ]. Furthermore, it associates with both G- and F-Actin and affects actin polymerization and actin turnover, influencing filopodia dynamics and arborization of neurons [ 2 ].

1. Identification and characterisation of Simiate, a novel protein linked to the fragile X syndrome. PLoS ONE 8, e83007
2. Simiate is an Actin binding protein involved in filopodia dynamics and arborization of neurons. Front Cell Neurosci 8, 99