InterPro domain: IPR039163

General Information

  • Identifier IPR039163
  • Description ER membrane protein complex subunit 7
  • Number of genes 145
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Abstract

ER membrane protein complex subunit 7 (EMC7) is a component of the endoplasmic reticulum membrane protein complex and may be involved in degradation of misfolded proteins by the ubiquitin- and proteasome-dependent process known as ER-associated degradation (ERAD)[ 1 ]. EMC7 has been misnamed C11orf3, but is more correctly named C15orf24 because the gene is actually on human chromosome 15.


1. Defining human ERAD networks through an integrative mapping strategy. Nat. Cell Biol. 14, 93-105

Species distribution

Gene table

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