InterPro domain: IPR039043

General Information

  • Identifier IPR039043
  • Description Zinc finger protein-like 1
  • Number of genes 157
  • Gene duplication stats Loading...

Abstract

ZFPL1 is a ring finger protein required for cis-Golgi integrity and efficient ER-to-Golgi transport [ 1 ]. It may have a role in regulating autophagy [ 2 ].


1. ZFPL1, a novel ring finger protein required for cis-Golgi integrity and efficient ER-to-Golgi transport. EMBO J. 27, 934-47
2. Knockdown of ZFPL1 results in increased autophagy and autophagy‑related cell death in NCI‑N87 and BGC‑823 human gastric carcinoma cell lines. Mol Med Rep 15, 2633-2642

Species distribution

Gene table