InterPro domain: IPR038898

General Information

  • Identifier IPR038898
  • Description BRO1 domain-containing protein BROX
  • Number of genes 333
  • Gene duplication stats Loading...

Abstract

BROX has a Bro1 domain-like sequence and a C-terminal thioester-linkage site of isoprenoid lipid (CAAX motif). It interacts with CHMP4, a component of endosomal sorting complex required for transport III [ 1 ].


1. Brox, a novel farnesylated Bro1 domain-containing protein that associates with charged multivesicular body protein 4 (CHMP4). FEBS J. 275, 682-92

Species distribution

Gene table