InterPro domain: IPR038894

General Information

  • Identifier IPR038894
  • Description X-ray radiation resistance-associated protein 1
  • Number of genes 6
  • Gene duplication stats Loading...
  • Associated GO terms GO:0010165  

Abstract

XRRA1 regulates the response of human tumour and normal cells to X-radiation (XR). It may be involved in a DNA damage response that drives radio- and chemoresistance by regulating the ATM/CHK1/2 pathway [ 1 ].


1. XRRA1 Targets ATM/CHK1/2-Mediated DNA Repair in Colorectal Cancer. Biomed Res Int 2017, 5718968

Species distribution

Gene table