InterPro domain: IPR038870
General Information
- Identifier IPR038870
- Description Ubiquitin-associated protein 1
- Number of genes 149
- Gene duplication stats Loading...
- Associated GO terms GO:0043130 GO:0043162 GO:0000813
Abstract
UBAP1 is a subunit of ESCRT-I, a complex facilitating endosomal sorting of ubiquitinated cargo [ 1 ]. It interacts with ubiquitin via a SOUBA domain [ 2 ].
1. UBAP1 is a component of an endosome-specific ESCRT-I complex that is essential for MVB sorting. Curr. Biol. 21, 1245-50
2. The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain. Structure 20, 414-28
Species distribution
Gene table
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