InterPro domain: IPR038716

This domain is found in the eukaryotic 60S ribosomal proteins P1 and P2, as well as in archaebacterial 50S ribosomal protein L12. It is involved in dimerization [ 1 ]. These proteins play an important role in the elongation step of protein synthesis [ 2 , 3 ].

1. Solution structure of the dimerization domain of the eukaryotic stalk P1/P2 complex reveals the structural organization of eukaryotic stalk complex. Nucleic Acids Res. 40, 3172-82
2. Three binding sites for stalk protein dimers are generally present in ribosomes from archaeal organism. J. Biol. Chem. 282, 32827-33
3. Structural basis for translation factor recruitment to the eukaryotic/archaeal ribosomes. J. Biol. Chem. 285, 4747-56