InterPro domain: IPR038551

A number of eukaryotic ribosomal proteins can be grouped on the basis of sequence similarities. One of these families, the S26E family, includes mammalian S26 [ 1 ]; Octopus S26 [ 2 ];Drosophila S26 (DS31) [ 3 ]; plant cytoplasmic S26; and fungal S26 [ 4 ]. S26 may be involved in the attachment of eIF3 and poly (U) [ 5 ]. Disruption of RPS26, the gene encoding a homologue of ribosomal protein small subunit S26 in yeast (S. cerevisiae), resulted in the formation of micro-colonies, suggesting that it is important for the normal cell growth of S. cerevisiae [ 5 ].

1. Molecular cloning and nucleotide sequence of DNA complementary to rat ribosomal protein S26 messenger RNA. J. Biochem. 97, 983-92
2. [Isolation and structural characteristics of cDNA for octopus proteins which are homologous to rat S26 ribosomal protein] Dokl. Akad. Nauk SSSR 304, 464-9
3. The nucleotide sequence of a gene for a putative ribosomal protein S31 of Drosophila. Nucleic Acids Res. 17, 2121
4. The Saccharomyces cerevisiae homologue of ribosomal protein S26. Gene 150, 401-2