InterPro domain: IPR038096

This superfamily represents a domain found in the Transcriptional enhancer factor (TEF) and in the Conidiophore development regulator aba.

The TEA domain is a DNA-binding region of about 66 to 68 amino acids that has been named after the two proteins that originally defined the domain: TEF-1 and abaA. The TEA domain is located toward the amino terminus of eukaryotic transcription factors of the TEA/ATTS family. It is predicted to contain three alpha-helices, two of which have been demonstrated to be important for DNA binding [ 1 ].

1. Characterization of the transcription activation function and the DNA binding domain of transcriptional enhancer factor-1. EMBO J. 12, 2337-48