InterPro domain: IPR037494
General Information
- Identifier IPR037494
- Description Rubisco accumulation factor 1
- Number of genes 129
- Gene duplication stats Loading...
Abstract
Ribulose-1,5-bis-phosphate carboxylase/oxygenase (Rubisco) is the rate-limiting carbon fixing enzyme of photosynthesis. Rubisco is a complex of eight large (RbcL) and eight small (RbcS) subunits that requires assembly chaperones. Rubisco accumulation factor 1 (Raf1) acts during Rubisco assembly [ 1 ]. It acts downstream of chaperonin-assisted RbcL folding by stabilizing RbcL antiparallel dimers for assembly into RbcL8 complexes with four Raf1 dimers bound. Raf1 displacement by RbcS results in holoenzyme formation [ 2 ].
1. Ribulose-1,5-bis-phosphate carboxylase/oxygenase accumulation factor1 is required for holoenzyme assembly in maize. Plant Cell 24, 3435-46
2. Structure and mechanism of the Rubisco-assembly chaperone Raf1. Nat. Struct. Mol. Biol. 22, 720-8