InterPro domain: IPR037473

Rubber oxygenase Lcp (for latex clearing protein) is involved in the initial step of rubber degradation [ 1 , 2 , 3 ]. It catalyses the extracellular cleavage of poly (cis-1,4-isoprene) in Gram-positive rubber degrading bacteria such as Streptomyces sp. K30 [ 4 , 4 , 5 ]. This family consists of Lcp, but also includes uncharacterised proteins from Gram-negative bacteria and fungi.

1. Importance of the latex-clearing protein (Lcp) for poly(cis-1,4-isoprene) rubber cleavage in Streptomyces sp. K30. Microbiologyopen 1, 13-24
2. Identification and characterization of genes from Streptomyces sp. strain K30 responsible for clear zone formation on natural rubber latex and poly(cis-1,4-isoprene) rubber degradation. Biomacromolecules 6, 180-8
3. Secretion and transcriptional regulation of the latex-clearing protein, Lcp, by the rubber-degrading bacterium Streptomyces sp. strain K30. Appl. Environ. Microbiol. 74, 5373-82
4. Structural and Functional Analysis of Latex Clearing Protein (Lcp) Provides Insight into the Enzymatic Cleavage of Rubber. Sci Rep 7, 6179
5. Latex Clearing Protein (Lcp) of Streptomyces sp. Strain K30 Is a b-Type Cytochrome and Differs from Rubber Oxygenase A (RoxA) in Its Biophysical Properties. Appl Environ Microbiol 81, 3793-9