InterPro domain: IPR037171

This entry is composed of multiple transferases, mainly ribose-5-phosphate isomerase A (RpiA), glucosamine-6-phosphate deaminase (NagB) and 6-phosphogluconolactonase (6PGL). RpiA and 6PGL are involved in the pentose phosphate pathway while NagB is involved in the last step of the N-acetylneuraminate degradation pathway. These enzymes share a common core alpha/beta structure [ 1 ].

1. Three dimensional structure and implications for the catalytic mechanism of 6-phosphogluconolactonase from Trypanosoma brucei. J. Mol. Biol. 366, 868-81